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[2024-12-02] We published a paper on origin of the habenular astrocytes in GLIA. [Post] [Fulltext]

[2024-11-05] A grad student Hattori-san published a paper in Medicine. [Link]

[2024-11-01] A collaborative study with Sakayori lab was published in J Nutr Sci Vitaminol. [Link]

[2024-10-19] Prof. Aizawa and Handa-san gave talks in a branch of Japanese association of anatomists at Yamaguchi.

[2024-09-06] Prof. Aizawa gave an invited talk for Social memory (Tohoku forum for creativity) in Sendai. [Link]

Our interests

Pathology underlying the mental and neurological disorders revealed by molecular analyses

Novel microscopes and devices for structural and functional analyses of the brain

We welcome the graduate students and research collaboration all over the world

Hidenori Aizawa

Hidenori Aizawa

Professor

Department of Neurobiology, Graduate School of Biomedical and Health Sciences, Hiroshima University

Principal investigator

Dr. Aizawa is the Professor of the Department of Neurobiology, Graduate School of Biomedical and Health Sciences, Hiroshima University. After training as a psychiatrist, Dr. Aizawa completed his Ph.D in Neuroanatomy at Chiba University. He joined Hitoshi Okamoto’s lab in RIKEN Brain Science Institute as a research scientist as well as deputy lab head and found evolutionarily conserved habenular pathways in vertebrate brain. He moved to the study on a role of the habenula in depression at Tokyo Medical and Dental University and Hiroshima University. His research interests include the molecular machinery underlying the pathophysiology of psychiatric and neurologic disorders.

We usually hold the weekly meeting on Friday for the journal club and progress report. In addition, neuroscience textbook is also dsicussed to help the beginners to learn the basics periodically, which we call neuroscience club.

If you are interested in joining our lab or collaborative project, please feel free to contact us via [Contact].

[Researchmap]

[ResearchGate]

[ORCID]

Interests
  • Mental disorders
  • Molecular biology
  • Neurophysiology
Education
  • PhD in Medicine, 2003

    Chiba University

  • MD, 1998

    Yamagata University

Lab members

Principal Investigators

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Hidenori Aizawa

Professor

Mental disorders, Molecular biology, Neurophysiology

Researchers

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Miho Matsumata

Assistant professor

Animal behavior, Genetic manipulation, Neurobiology

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Takashi Handa

Assistant professor

Electrophysiology, Two photon microscopy, Animal behaviors

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Deepa Kamath Kasaragod

Assistant professor

Optics, Microscopy, Imaging

Grad Students

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Laura Ayaka Noguera Oishi

Grad student

Histology, Molecular biology, Imaging

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Qing Zhang

Grad Student

Electrophysiology, Data science, Neurology

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Yuki Hattori

Grad Student

Critical medicine, Sepsis, Spreading depolarization

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Zhongqi Ma

Grad Student

Electrophysiology, Data science, Depression

Administration

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Nobuhiro Nakatani

Technical staff

Histology, Acrylic handicraft

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Yuka Ishimaru

Assistant

Molecular biology, Mouse genetics

Visitors

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Hidenori Takemoto

Visitors

Rehabilitation, Imaging, Histology

Alumni

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Xintong Yao

Grad Student

Behavior, Depression, Limbic system

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Feng Miao

Grad student

Stress, Electrophysiology, Optical recording

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Lei Li

Grad student

Spreading depolarization, Molecular biology, Imaging

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Meina Zhu

Postdoc

Neurology, Basal ganglia, Circulation

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Mayeso Naomi Gwedela

Lecturer

Epilepsy, Zebrafish, Herbal medicine

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Kazuya Kikutani

Assistant Professor

Critical Care, Sepsis, Neuroinflammation

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Haruhi Terai

Researcher

Neural development, Spreading depression, Migraine

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Wanqin Tan

Grad Student

Genetics, Neural circuit, Histology

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Hiroshi Giga

Chief of staffs

Critical Care, Sepsis, Neuroinflammation

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Hikaru Ito

Associate professor

Cell biology, Neuroinflammation, Glia

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Kanako Nozaki

Assistant professor

Neuroinflammation, Stress, Depression

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Takashi Nakano

Associate professor

Monoamines, Data science, Computational neuroscience

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Wanpeng Cui

Postdoc

Monoamines, Glia, Depression

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Fumie Nishimura

Assistant

Lab management, Mouse genetics

Research

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Habenula Project

Habenula Project

Study upon a role of the habenula regulating monoamines metabolism in depression

Spreading Depression Project

Spreading Depression Project

What happens when you meet brain injury? Spreading killer waves of neural excitation is under investigation.

Sepsis Project

Sepsis Project

How do we save our brain from systemic inflammation?

3D Microscopy Project

3D Microscopy Project

We are developing the fluorescent microscope which allows us to reveal the neural structure three-dimensionally.

Medicinal Herbs Project

Medicinal Herbs Project

Pharmacological effect of medicinal herbs in Malawi is examined using zebrafish as a model.

Manupulation of the neural circuit

Manupulation of the neural circuit

Genetics allows the activation and inhibition of the specific cell types and pathway to disentangle the pathophysiology underlying psychiatric and neurological disorders.

Animal models for disorders in the brain

Animal models for disorders in the brain

Animal models for the human disease is dispensable for molecular and cellular analysis for development of the novel diagnostics and therapeutics.

Recent Publications

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Journal Club

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