Summary of journal club

NDNF interneurons in layer 1 gain-modulate whole cortical columns according to an animal’s behavioral state

Cellular mechanisms underlying processing of sensory information in neural circuits in animal’s behavioral state-dependent.

Light entrainment affecting the mood and cognitive functions via retinal projection

Intrisically photosensitive retinal cells mediate the effect of light on mood and cognitive modulation as revealed in mice study.

Spreading depolarization stops focal seizures from becoming generalized

A mouse study showing the role of spreading depression in preventing seizure generalization

Exploring the specific time course of interhemispheric inhibition between the human primary sensory cortices

An attempt to understand the neurophysiological mechanism of interhemispheric inhibition (IHI) between the human primary sensory cortices.

Striosome-based map of the mouse striatum that is conformable to both cortical afferent topography and uneven distributions of dopamine D1 and D2 receptor-expressing cells

Striosome-based map of the mouse striatum that is conformable to both cortical afferent topography and uneven distributions of dopamine D1 and D2 receptor-expressing cells

Aging alters configuration of fast- and slow-twitch fibers associated with muscle fiber denervation.

Differential modulation of slow and fast muscles by aging and its underlying mechanism

Prolonged mechanical ventilation-induced neuroinflammation affects postoperative memory dysfunction in surgical mice

Prolonged mechanical ventilation after surgery further aggravates cognitive decline that may derive from upregulation of inflammatory response, activation of glia and ultrastructural changes of synapses in the hippocampus.

Precisely timed dopamine signals establish distinct kinematic representations of skilled movements

Determine the effects of precisely timed dopamine manipulations on the performance of a complex, finely coordinated dexterous skill.

Nucleus Accumbens Microcircuit Underlying D2-MSN-Driven Increase in Motivation

This study reveals for the first time how D2-MSN stimulation can modulate downstream regions and local microcircuit to increase motivation.

Accumulation of major oxidized base among the nucleotide pool in the aged brain

A study showing a sexually dimorphic role of 8-oxoguanine accumulation in neurogenesis in aged brain